Cancer Driver Genes: Methods and Protocols – eBook

This ebook, Cancer Driver Genes: Methods and Protocols (PDF) presents protocols for the identification of genetic drivers of cancer. Chapters guide readers through a brief history of cancer gene discovery, in vitro approaches, in silico approaches, and in vivo approaches using forward genetic screens in mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Cancer Driver Genes: Methods and Protocols aims to provide protocols that will be used and adapted by cancer researchers to expand the knowledge base of molecular mechanisms contributing to the progression, initiation, and metastasis of cancer.